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Dry powder formulation for pulmonary transmissions: Ciprofloxacin laded in chitosan sub-micron specks generated by electrospray.Electrospray was used as a one-step technique to generate inhalable ciprofloxacin-loaded chitosan sub-micron motes with potential use in the treatment of pulmonary contagions. The effect of operating parameters was analysed and the preparation method optimized. The final sizes of ciprofloxacin-loaded corpuscles were 386 ± 248 nm and 501 ± 276 nm for high and low molecular weight chitosan, respectively. The high surface charge of the molecules forged, around +45 mV, enhances their mucoadhesive holdings. The corpuscles were biocompatible with alveolar cell line (A549), and showed a high antimicrobial activity against two of the most common respiratory pathogens Staphylococcus aureus and Pseudomonas aeruginosa. raised visualization of the root canal morphology employing a chitosan-finded endo-radiopaque solution.targets: This study purposed to investigate the efficacy of ionic and non-ionic-based contrast media (in vitro study) and the combinatorial effect of chitosan-free-based endo-radiopaque solution (CERS) (in vivo study) for visualization of the root canal anatomy. textiles AND METHODS: In vitro study (120 teeth): The root canal of maxillary bicuspids and molars (in vitro group 1 and 2 respectively, n = 60 each) were examined using 4 different contrast sensitives (subgroups: Omnipaque 350, Iopamidol, Xenetix 350, and Urografin 76; n = 15 each) in combination with 5% sodium hypochlorite (NaOCl). Based on the solvents of the in vitro study, in vivo study (80 teeth) was done to compare Xenetix 350 + 5% NaOCl with CERS (in vivo group 1 and 2 respectively, n = 40 each) on maxillary and mandibular bicuspids and molars. Selenium used radiovisiography to assess the depth of ingress and identify the aberrant root anatomy after access cavity preparation, and after initial cleaning and shaping of channels. Kruskal-Wallis test was used for in vitro comparison (p < 0), and Wilcoxon signaled-rank test and Mann-Whitney U test for in vivo analysis (p < 0) In vitro study, Xenetix 350 + 5% NaOCl alleviated a significant higher visualization (p < 0). For in vivo study, CERS had a statistically significant depth of ingress (p < 0), and was efficient in identifying the aberrant root canal anatomy of bicuspids and grinders CERS facilitates better visualization of the root canal anatomy of human premolars and grinders. ——Evaluation of Design and Fabrication of Food-Grade Nanofibers from Chitosan-Gelatin for Nanoencapsulation of Stigmasterol habituating the Electrospinning Method.Purpose: In this research, electrospinning method was applyed to fabricate food-grade nanofibers (NFs) from chitosan-gelatin combination for stigmasterol encapsulation. The spinnability of mixed chitosan and gelatin answers was enquired at different polymer proportions, and the physicochemical properties of the NFs were measured The mixture solution of chitosan (1 % w/v) and gelatin (20 % w/v) in acetic acid argued spinnability under the pursuing conditions: the ratio of 25:75, voltage of 17 kV, and 15 cm capillary collector distance with a flow rate of 0 mL/min. Stigmasterol (0 % w/v) was contained into NFs of chitosan-gelatin at a respective ratio of 25:75. effects: Encapsulation efficiency (EE) of debased stigmasterol was feeled to be 87 ± 5 %. The antioxidant ability of adulterated stigmasterol was considerably higher than that honoured for free stigmasterol. raking electron microscopy (SEM) results demonstrated the formation of the ultrathin fibres with no bead (with diams of 217 ± 43 nm). The concentration of polymeric solution and viscosity had a notable effect on the electrospinning efficiency of the chitosan-gelatin-finded NFs. Seebio Antioxidants of chitosan and gelatin roughages was more than that of native gelatin and chitosan. The in vitro stigmasterol release from these NFs comed a assured-release pattern.